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@article{Musa_Sallau_Oyewale_Ali_Kabir_2023, title={Isolation, Characterization and Evaluation of Anti-schistosomal Activity of triterpenes from crude ethyl acetate extract of the Rhizome of Dolichos pachyrhizus}, volume={4}, url={https://ajhse.org/index.php/ajhse/article/view/424}, DOI={10.52417/ajhse.v4i1.424}, abstractNote={<p>Schistosomiasis is a neglected tropical disease caused by helminth flatworms of the genus Schistosoma. Currently, praziquantel is the only medication available. Schistosomiasis is the second most deadly parasitic infection after malaria. <em>Dolichos pachyrhizus</em>’s (Fabaceae) rhizome is commonly utilized as an antihelmintic. In this study, the in vitro antischistosomal activity of <em>D. pachyrhizus </em>crude extract and isolated compounds were examined against S. mansoni immature worms. All mature and immature worms were killed by C1, C2 and ethyl acetate extract at 500 mg/mL after 24 h incubation. Additionally, all the examined compounds and extract at 500 mg/mL exponentially reduced the parasite’s movement; (70-90 %) shrinkage, viability (10-30 %) and mortality (70-90 %) rates.</p> <p> </p>}, number={1}, journal={African Journal of Health, Safety and Environment}, author={Musa, N. M. and Sallau, M. S. and Oyewale, A. O. and Ali, T. and Kabir, S.}, year={2023}, month={Jun.}, pages={117-131} }
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