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@article{AINA_OLALEYE_2024, title={NASAL CARRIAGE OF ANTIBIOTICS RESISTANT Staphylococcus aureus AMONG MEDICAL STUDENTS OF OBAFEMI AWOLOWO UNIVERSITY, ILE-IFE, SOUTH-WEST, NIGERIA.}, volume={5}, url={https://ajhse.org/index.php/ajhse/article/view/437}, DOI={10.52417/ajhse.v5i1.437}, abstractNote={&lt;p&gt;The nose is a recognized source of &lt;em&gt;Staphylococcus aureus&lt;/em&gt; which is a common pathogenic microbe in humans which cause different infections in hospitals as well as in the community. This study determined the nasal carriage and the antibiotic resistance profile of &lt;em&gt;Staphylococcus aureus&lt;/em&gt; among the female medical students of Obafemi Awolowo University (OAU), Ile-Ife, Osun State, Nigeria. Eighty nasal samples, collected from 20 students were screened for mannitol fermentation, coagulase and catalase syntheses and Gram staining. Antibiotics resistance profile of the isolates was investigated using disc diffusion method. Out of the 80 samples screened, 25 isolates tested positive for mannitol fermentation and Gram staining. Twenty isolates tested positive for coagulase and catalase syntheses confirming them to be &lt;em&gt;Staphylococcus aureus&lt;/em&gt; while five tested negative to coagulase and catalase syntheses. Eleven students were intermittent carriers of &lt;em&gt;S. aureus&lt;/em&gt;, seven were non-carriers while two were persistent carriers of &lt;em&gt;S.aureus&lt;/em&gt; during the period of investigation. Antibiotic sensitivity test revealed that all the 20 isolates were sensitive to streptomycin and ciprofloxacin,19 isolates showed resistance to cefotaxime and 9 isolates showed multiple resistance to co-amoxiclav, ampicillin, cloxacillin and cefotaxime while 1 isolate showed multiple resistance to co-amoxiclav, cloxacillin, cotrimoxazole and partially resistant to cefotaxime. In conclusion, there was detection of multiple antibiotics resistant &lt;em&gt;Staphylococcus aureus&lt;/em&gt; among female medical students of OAU who frequently visit teaching hospital for their clinical trainings; this could lead to a major challenge in the management of staphylococcal infections in the hospital and the development of both community acquired and nosocomial infections.&lt;/p&#38;gt;}, number={1}, journal={African Journal of Health, Safety and Environment}, author={AINA, O.R. and OLALEYE, O.N.}, year={2024}, month={Mar.}, pages={35-42} }<hr>
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